Volume : 4, Issue : 3, MAR 2018

NANO-LIQUID CHROMATOGRAPHY AND ITS PHARMACEUTICAL APPLICATIONS

SHEABA MARIAM SHAJI*, MRS. RUBY PHILIP, DR. ELESSY ABRAHAM

Abstract

Chromatography may be defined as a method of separating a mixture of components into individual components through equilibrium distribution between two phases. It is a non-destructive procedure for resolving a multi-component mixture of trace, minor or major constituents into its individual fractions. Different variations may be applied to solids, liquids and gases. Chromatography can be used for qualitative and quantitative analysis. Quantitative analysis can be carried out by measuring the area of the chromatographic peak. Nano-liquid chromatography (nano-LC), microchip devices and nano-capillary electrophoresis are miniaturized methods that minimize reagent consumption and waste generation. Nano-LC has great potential to become an indispensable tool for routine analysis of biomolecules.

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References

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