Volume : 1, Issue : 1, NOV 2015


Asif Husain


A series of 3-arylidene-5(4-substituted phenyl)-2(3H)-pyrrolones have been evaluated for their in vitro anthelmintic activity against two species
of earthworms i.e. Pheretima posthuma and Perionyx excavatus. The anthelmintic activity of seven pyrrolones (1-7) was determined by recording
the mean paralyzing and death times of the worms at concentration of 2mg/mL. The screened compounds showed appreciable anthelmintic
activities against both types of worms.


Nitrogen heterocycles, Pheretima posthuma, Perionyx excavatus, Anthelmintic.

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