Volume : 9, Issue : 1, JAN 2023

A REVIEW ON POLYCYSTIC OVARIAN SYNDROME: ITíS ASSOCIATION WITH REPRODUCTIVE AND METABOLIC MANIFESTATIONS

CHUMI DAS, JUMI DAS

Abstract

Polycystic ovarian syndrome (PCOS) is an endocrine disorder affecting many women of childbearing age. PCOS is a multifaceted lifestyle disorder characterized by various clinical manifestations like menstrual irregularity, reproductive infertility, hyperandrogenism, hirsutism, metabolic insulin resistance, diabetes mellitus and also various psychological features. But yet, the exact etiology of the disorder is not known till date. Literature was searched from Google scholar and PubMed. It affects 8% to 13% of reproductive women and is associated with reproductive and metabolic dysfunction. And the prevalence range mainly depends the methods applied and the studies based on Rotterdam criteria shows higher prevalence rate than any other methods. Genetic and environment contributes to the pathophysiology of the disease. Obesity worsens the presentation of PCOS and weight management and is proposed to be an initial strategy along with lifestyle modifications, dietary intake habit and physical exercises. Lifestyle modifications aimed at normalizing insulin resistance, improving androgen status and aiding weight management is recognized as a crucial initial treatment strategy. Monitoring and management of long term metabolic complications is also an important part of routine clinical care. Further research is required in this complex condition, emphasizing on lifestyle management as more and more cases has been rising in India till date.

Keywords

POLYCYSTIC OVARIAN SYNDROME, INSULIN RESISTANCE, INFERTILITY, MENSTRUAL IRREGULARITY, LIFESTYLE, DEPRESSION, ANXIETY.

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